The NOAA Chesapeake Bay Office is located in the Eastport section of Annapolis across Spa Creek from the Annapolis Harbor. It is approximately 30 miles from Baltimore or Washington. The nearest major airport is Baltimore-Washington International (BWI). Limo service is available between downtown Annapolis and BWI and Reagan National (Washington—DCA) Airports (Airport Sedan 410-760-3227).

• From the west (Washington, D.C), take Route 50 eastbound from the Washington Beltway (I-95/495) to Exit 24, Annapolis/Rowe Blvd.
• From the east (Maryland Eastern Shore via the Bay Bridge), take Route 50 westbound to Exit 24, Annapolis/Rowe Blvd; be sure to stay off to the right at the exit and do not go onto Bestgate Road.
• From the north (Baltimore), take I-97 to Route 50 eastbound just west of exit 24.
• Once you exit Route 50, take Rowe Blvd. until it forks, and bear right onto Northwest Street and follow it through one stoplight until it ends at Church Circle. Take a right onto Church Circle and stay in the outer part of the circle.
• Exit right onto Duke of Gloucester St. (at light between Maryland National Bank and Maryland Inn). Take Duke of Gloucester St. until it ends at stop sign, staying in right lane. Turn right to go over the bridge, and stay in the left lane after the bridge. Take first left, at stoplight, onto Severn Ave. Go 1 1/2 blocks and turn left into the Annapolis City Marina pay parking lot, or use free street parking.
• The NOAA Chesapeake Bay Office and conference room is on the first floor of the A Building next to Carrol's Creek Cafe. The Chesapeake Bay Program Office is in B Building, and the Bay Program Conference room is in C Building.